Genetically targeted anatomical and behavioral characterization of the cornu ammonis 2 (CA2) subfield of the mouse hippocampus
نویسنده
چکیده
Genetically targeted anatomical and behavioral characterization of the cornu ammonis 2 (CA2) subfield of the mouse hippocampus
منابع مشابه
Stereological analysis of cornu ammonis in prenatally stressed rats: a heuristic neurodevelopmental model of schizophrenia
Objective(s):The hippocampus has been implicated in pathophysiology of schizophrenia. Prenatal stress is a contributing risk factor for a wide variety of neuropsychiatric diseases including schizophrenia. This study examined long-term effects of prenatal restraint stress on the stereological parameters in the Cornu Ammonis (CA) of adult male rats as an animal model of schizophrenia. Materials ...
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Objective(s):Growing evidence indicates that extract of Ginkgo biloba (EGb) attenuates hippocampal-dependent memory deficit in aged individuals; however, very little is known about the effect of EGb on the structure of hippocampus. Therefore we examined the EGb-induced morphological changes of the Cornu Ammonis (CA) region in aged rats. Materials and Methods: Sixteen aged male Wistar rats, 24 ...
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The hippocampal cornu ammonis 2 (CA2) region is unique in being the only CA region receiving inputs from the hypothalamic supramammillary nucleus, of importance in modulating hippocampal theta rhythm, and is seizure resistant in temporal lobe epilepsy. CA2 has, however, been little studied, possibly because of its small size and difficulty encountered in defining its borders. To investigate the...
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Objective(s):This study was carried out to evaluate the effect of maternal morphine exposure during gestational and lactation period on pyramidal neurons of hippocampus in 18 and 32 day mice offspring. Materials and Methods: Thirty female mice were randomly allocated into cases and controls. In case group, animals received morphinesulfate 10 mg/kg.body weight intraperitoneally during 7 days bef...
متن کاملMagnetic resonance scanning and image segmentation procedure at 3 T for volumetry of human hippocampal subfields
BACKGROUND: Recent evidence suggests that dementia affects hippocampal substructures differentially and thus identifying anatomical details of this structure is potentially clinically important. Visualising details of human hippocampal substructures in vivo is challenging by imaging due to the small size of the medial temporal lobe structure. METHODS: MRI data were acquired with a 3 T MR scanne...
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